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Publications

• Cusin C., Dillon D.G., Belleau E., Normandin M.D., Petibon Y., El-Fakri G., Dhaynaut M., Hooker J., Kaptchuk T., McKee M., Hayden E., Meyer A., Jahan A., Origlio J., Ang Y-S., Brunner D., Kang M., Long Y., Fava M., Pizzagalli D.A. (In Press). Novel multi-modal methodology to investigate placebo response in major depressive disorder. Journal of Affective Disorders.

• Han M.X., Nadarajan R., Wang N., Kee M.Z.L., Lim S., Sagar Y.K., Chow B., Tan A.P., Cheon B.K., Ang Y-S., Zhou J.H., Chen H.Y., Chong Y.S., Gluckman P.D., Meaney M.J., Law E.C. (In Press). Maternal depressive symptoms and risk for childhood depression: role of executive functions. Journal of the American Academy of Child and Adolescent Psychiatry.

• Kangas B., Ang Y-S., Short A.K., Baram T., Pizzagalli D.A. (In Press). Computational Modeling Differentiates Learning Rate from Reward Sensitivity Deficits Produced by Early Life Adversity in a Rodent Touchscreen Probabilistic Reward Task. Biological Psychiatry: Global Open Science.

• Gigli V., Castellano P., Ghezzi V., Ang Y-S., Schettino M., Pizzagalli D.A., Ottaviani C. (In Press). Daily social isolation maps onto distinctive features of anhedonic behavior: A combined ecological and computational investigation. Biological Psychiatry: Global Open Science.

• Dillon D.G., Belleau E.B., Origlio J., McKee M., Jahan A., Meyer A., Souther M.K., Brunner D., Kuhn M., Ang Y-S., Cusin C., Fava M., Pizzagalli D.A. (In Press). Using drift diffusion and RL models to disentangle effects of depression on decision-making vs. learning in the probabilistic reward task. Computational Psychiatry.

• Anant N., Kaur D., Nadarajan R., Phua D.Y., Yap S.C., Gluckman P.D., Yap F., Chen H., Broekman B., Meaney M.J., Ang Y-S. (2023). Validating the Children’s Depression Inventory-2: Results from the Growing Up in Singapore Towards Healthy Outcomes (GUSTO) study. PLoS One. (Article)

• Castellano P., Gigli V., Schettino M., Ghezzi V., Ang Y-S., Pizzagalli D.A., Ottaviani C. (2022). COVID-19 consequences on motivational functioning: an ecological investigation of the role of momentary gustative-olfactory sensitivity and tonic heart rate variability. Neuroscience Applied. (Article)

• Ang Y-S., Gelda S., Pizzagalli D.A. Cognitive effort-based decision making in Major Depressive Disorder. (2022). Psychological Medicine. (Article)

• Ang Y-S, Cusin C., Petibon Y., Dillon D.G., Breiger M., Belleau E.L., Normandin M., Schroder H., Boyden S., Hayden E., Levine T., Jahan A., Meyer A.K., Kang, M-S. Brunner D., Gelda S.E., Hooker J., El Fakhri G., Fava M., Pizzagalli D.A. (2022). A multi-pronged investigation of option generation using depression, PET and modafinil. Brain. (Article)

• Klar V.S., Ang Y-S., Lockwood P., Attaallah B., Dickson S., Drew D., Kienast A., Maio M.R., Plant O., Slavkova E., Toniolo S., Zambellas R., Irani S.R., Husain M. (2022). Assessment of apathy in neurological patients using the Apathy Motivation Index caregiver version. Journal of Neuropsychology. (Article)

• Schettino M., Ghezzi V., Ang Y-S., Duda J.M., Fagioli S., Mennin D.S., Pizzagalli D.A., Ottaviani O. (2022). Perseverative Cognition in the Positive Valence Systems: An Experimental and Ecological Investigation. Brain Sciences. (Article)

• Suthaharan P., Corlett P., Ang Y-S. (2021). Computational modeling of behavioral tasks: An illustration on a classic reinforcement learning paradigm. The Quantative Methods for Psychology. (Article)

• Ang Y-S., Pizzagalli D.A. (2021). Predictors of treatment outcome in adolescent depression. Current Treatment Options in Psychiatry. (Invited review) (Article)

• Belleau E.L., Kremens R., Ang Y-S., Pisoni A., Bondy E., Auerbach R.P., Pizzagalli D.A. Reward Functioning Abnormalities in Adolescents at High Familial Risk for Major Depressive Disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. (Article)

• Ang Y-S., Frontero N., Belleau E., Pizzagalli D.A. (2020) Disentangling vulnerability, state and trait features of neurocognitive impairments in depression. Brain. (Article)

• Ang Y-S., Bruder G.E., Keilp J.G., Rutherford A., Alschuler D.M., Pechtel P., Webb C.A., Carmody T., Fava M., Cusin C., McGrath P.J., Weissman M., Parsey R., Oquendo M.A., McInnis M.G., Cooper C.M., Deldin P., Trivedi M.H., Pizzagalli D.A. (2022). An exploration of baseline and early changes in neurocognitive characteristics as predictors of treatment response to bupropion, sertraline and placebo in the EMBARC Clinical Trial. Psychological Medicine. (Article)

• Pizzagalli D.A., Smoski M., Ang Y-S., Whitton A.E., Sanacora G., Mathew S.J., Nurnberger J., Lisanby S.H., Iosifescu D.V., Murrough J.W., Yang H., Weiner R.D., Calabrese J.R., Goodman W., Potter W.Z., Krystal A.D. (2020). Selective Kappa Opioid Antagonism Ameliorates Anhedonic Behavior: Evidence from the Fast-Fail Trial in Mood and Anxiety Spectrum Disorders. Neuropsychopharmacology. (Article)

• Ang Y-S., Kaiser R., Deckersbach T., Almeida J., Phillips M.L., Chase H.W., Webb C.A., Parsey R., Fava M., McGrath P., Weissman M., Adams P., Deldin P., Oquendo M.A., McInnis M.G., Carmody T., Bruder G., Cooper C.M., Chin Fatt C.R., Trivedi M.H., Pizzagalli D.A. (2020). Pretreatment reward sensitivity and frontostriatal resting-state functional connectivity are associated with response to bupropion after sertraline non-response. Biological Psychiatry. (Article)

• Le Heron C., Kolling N., Plant O., Kienast A., Janska R., Ang Y-S., Fallon S.J., Husain M., Matthew M.A.J. (2020). Dopamine and motivational state drive dynamics of human decision making. Journal of Neuroscience. (Article)

• Whitton A., Reinen J., Slifstein M., Ang Y-S., McGrath J., Iosifescu D., Dargham A., Pizzagalli D., Schneier F. (2020). Baseline reward processing and ventrostriatal dopamine function is associated with pramiprexole response in depression. Brain. (Article)

• Fallon S.J., Kienast A., Muhammed K., Ang Y-S., Manohar S., Husain M. (2019). Dopamine D2 receptor stimulation modulates the balance between ignoring and updating according to baseline working memory ability. Journal of Psychopharmacology. (Article)

• Ang Y-S., Pizzagalli D.A. (2019). Understanding Personal Control and the Brain Reward System for Psychopathology is Challenging but Important. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. (Article)

• Ang Y-S.*, Manohar S.*, Plant O., Kienast A., Le Heron C., Muhammed K., Hu M., Husain M. (2018). Dopamine modulates option generation for behaviour. Current Biology. (Article)

• Le Heron C., Plant O., Manohar S., Ang Y-S., Jackson M., Lennox G., Husain M. (2018). Distinct effects of dopamine and apathy on effort based decision making in Parkinson’s disease. Brain. (Article)

• Ang Y-S., Lockwood P., Kienast A., Plant O., Drew D., Slavkova E., Tamm M., Husain M. (2018). Differential impact of behavioural, social and emotional apathy on Parkinson’s disease. Annals of Clinical and Translational Neurology. (Article)

• Boyle C.C., Dooley L.N., Kuhlman K.R., Haydon M.D., Nooteboom P., Robles T.F., Ang Y-S., Pizzagalli D.A., Bower J.E. (2018). Inflammation and dimensions of reward processing. Psychoneuroendocrinology. (Article) (Editor’s choice article for the issue)

• Fallon S.J., Muhammed K., Drew D.S., Ang Y-S., Manohar S., Husain M. (2018). Dopamine guides competition for cognitive control: Common effects of haloperidol on working memory and response conflict. Cortex. (Article)

• Ang Y-S.*, Lockwood P.*, Apps M.A.J., Muhammed K., Husain M. (2017). Distinct subtypes of apathy revealed by the Apathy Motivation Index. PLoS One. (Article)

• Lockwood P.*, Ang Y-S.*, Crockett M., Husain M. (2017). Motivated empathy: associations between empathy and apathy-motivation. in healthy people. Scientific Reports. (Article)

• Ang Y-S., Manohar S., Apps M.A.J. (2015). Commentary: Noradrenaline and Dopamine Neurons in the Reward/Effort Trade-off: A Direct Electrophysiological Comparison in Behaving Monkeys. Frontiers in Behavioural Neuroscience. (Article)

Technology Disclosures/Patents

• Ang Y-S, Y Chen (2023). A web-based application for automated computation of creativity from the option generation test.

• Ang Y-S, Lan L, Wong CK, Yue JYZ (2022). A mobile application for assessment of cognitive effort-based decision-making in humans.